Medical history isn't a text chunk.
It's an evolving graph.

Standard AI tools chop PDFs into isolated paragraphs and lose chronological state across encounters. CareNote connects every lab panel, prescription, discharge summary, and specialist consult into a persistent patient graph with a clickable PaperTrail linking every claim to its source page.

Explore Live Proof ↓
RK
Patient R.K.74y · Male · 5 Clinical Records Indexed (2024–2025)
3 supported1 conflicting1 not documentedINTERACTIVE CLINICAL PROOF
FLAGGED SAFETY CONCERNS
HIGH

Active 3-Drug Prescribing Cascade & Chart Lore: Furosemide 40 mg + KCl 20 mEq ongoing for copy-forwarded "HFpEF" despite normal Echo/NT-proBNP (#p.2), triggered by Amlodipine 10 mg vasodilatory edema.

HIGH

Unclosed Post-Discharge Hold (notable_absence): Temporary AKI hold on Empagliflozin 10 mg (#p.3) never closed despite renal recovery to baseline (Cr 1.12 mg/dL on 2025-03-04, #p.1).

Longitudinal Clinical Synthesis · PaperTrail Verified

Click any citation badge to inspect source

Five weeks after Primary Care initiated Amlodipine 10 mg daily , Patient R.K. developed bilateral ankle edema that Urgent Care misattributed to new-onset heart failure (“HFpEF”) and treated with Furosemide 40 mg daily . Although confirmatory echocardiography and NT-proBNP (58 pg/mL, LVEF 62%) ruled out heart failure 6 days later, the unverified “HFpEF” label was copy-pasted forward across subsequent encounters .

Unnecessary loop diuresis for dihydropyridine CCB vasodilatory edema precipitated orthostatic syncope, prerenal AKI (eGFR 64 → 36 mL/min), and hypokalemia (K+ 3.1 mEq/L), prompting inpatient addition of KCl 20 mEq and a conditional hold on Empagliflozin 10 mg until Cr <1.2 mg/dL . Despite creatinine recovering to 1.12 mg/dL on 04 Mar 2025, Empagliflozin remains unresumed .

Reconciled Causal Regimen & Loop State

Multi-Hop Graph State

PaperTrail Inspector

Zero blind trust · Exact source anchor

Claim #c3

Echo_Cardio_Nov2024.pdf

Diagnostic Report · 2024-11-25

Page 2

Cross-Record Contradiction (Chart Lore vs. Echo):

“TTE & Biomarker Conclusion: LVEF 62%, normal LV diastolic filling (E/e' 7.2), normal LA volume, NT-proBNP 58 pg/mL (ref <125). No evidence of heart failure; ankle edema consistent with dihydropyridine CCB vasodilation.”
Verification Status:⚡ CONFLICTING (CHART LORE)
Why 1D trend trackers miss this: A flowsheet only shows creatinine rising and falling. CareNote's bi-temporal graph links the Amlodipine → Furosemide → KCl prescribing cascade, refutes copy-pasted “HFpEF” chart lore against the normal Echo PDF (#p.2), and flags the unclosed Empagliflozin holdonce Cr recovered <1.2 mg/dL.

Vector databases are temporally blind.

Standard AI tools slice clinical PDFs into isolated text chunks and retrieve by semantic similarity in an eternal present. Because vector search lacks a model of chronological validity intervals, it retrieves superseded regimens alongside active orders, confuses historical chart lore with current diagnoses, and cannot trace multi-encounter prescribing cascades.

How Standard AI Tools Store Clinical Records (Vector Chunks)

Encounter records are broken into stateless fragments and indexed by keyword similarity. Retrieval repeats copy-pasted problem list labels (“chart lore”) and treats iatrogenic prescribing cascades as independent chronic conditions.

× Chunk 19 (Urgent Care): "Pedal edema: suspect HFpEF; start Furosemide 40mg"

× Chunk 44 (Discharge): "PMH: HFpEF. K+ 3.1; start KCl 20mEq. Hold Empagliflozin"

× Chunk 61 (Echo PDF): "LVEF 62%, NT-proBNP 58 pg/mL: no heart failure"

Result: Affirms copy-forwarded “HFpEF” chart lore, misses that Furosemide and KCl were triggered by Amlodipine edema, and drops the conditional Empagliflozin hold.

How CareNote Indexes Clinical Records (Bi-Temporal Knowledge Graph)

Aligns causal and epistemic edges across encounters and specialties. Links drug initiations to downstream symptoms, verifies copied diagnoses against primary diagnostic reports, and tracks conditional holds until closure.

Amlodipine 10mg → Edema → Furosemide → KCl → [PRESCRIBING CASCADE]

"HFpEF" Label vs. Normal Echo/BNP (#p.2) → [⚡ CHART LORE REFUTED]

Empagliflozin 10mg (Cr 1.12 < 1.2 threshold met) → [∅ UNCLOSED HOLD]

Result: Exposes the 3-drug iatrogenic cascade, refutes unverified chart lore via page-level Echo provenance, and surfaces the unclosed post-discharge hold.

Never trust an AI synthesis without a page number.

In medicine, a hallucinated dosage or misattributed date carries real danger. CareNote refuses black-box generation. Every asserted fact carries a direct audit anchor.

1. Fact Extraction

Multimodal AI reads the PDF visually, extracting values, units, reference intervals, and physical page numbers directly from the clinical record.

2. Graph Synthesis

Facts accumulate into the patient graph, connecting changes across visits and detecting discrepancies between different specialists.

3. Direct Audit Trail

Every claim in the clinical synthesis links directly to its source PDF. Click the citation to inspect the original doctor's note and page.

Query longitudinal clinical memory in plain language.

Ask questions across accumulated clinical encounter records. Receive grounded answers with direct PaperTrail citations back to the exact source PDF page.

“Why was Furosemide started, and did the echocardiogram ever confirm heart failure?”
“Is there a prescribing cascade behind his Jan 2025 AKI and potassium supplement?”
“Were any home medications held during admission that meet criteria to resume?”
Clinical Query Output · Patient R.K.Source-Grounded
User: "Why was Furosemide started, and did the echo confirm heart failure?"

No. Echocardiography ruled out heart failure; Furosemide was initiated in a prescribing cascade:

  • Cascade Origin: Bilateral ankle edema began 5 weeks after starting Amlodipine 10 mg daily PCP_Annual_Oct2024.pdf #p.2, and Urgent Care started Furosemide 40 mg for suspected “HFpEF” UrgentCare_Nov2024.pdf #p.1.
  • Chart Lore Refuted: Confirmatory TTE & biomarker 6 days later showed LVEF 62%, normal diastolic filling, and NT-proBNP 58 pg/mL (no heart failure) ⚡ Echo_Cardio_Nov2024.pdf #p.2.
  • Unclosed Hold: Subsequent diuretic-induced AKI prompted a temporary hold on Empagliflozin 10 mg until Cr <1.2 mg/dL Hospital_Discharge_Jan2025.pdf #p.3; Cr recovered to 1.12 mg/dL in March 2025 without resumption ∅ Outpatient_Labs_Mar2025.pdf #p.1.

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